This blog is dedicated to dental health and how it relates to a person's overall health. I will post articles and subjects relevant to today's most forward thinking on dental health, beauty, and comfort. Your participation and comemnts are welcomed in order to enrich the experience. Dr. Neal
Saturday, August 17, 2013
Gum Disease and Colon Cancer- Crystal Lake Dentist
Colon Cancer is Common and Deadly
It is the
second leading cause of death by cancer in the United States. . In 2009, the most recent year data was available, 136,717 people in the United
States were diagnosed with the disease.Overall, the lifetime risk of developing colorectal cancer is about 1 in
Gum Disease and
The connection is Fusobacterium nucleatum. Fusobacterium
nucleatum is an oral bacteria, common to the human oral cavity, that plays a role in periodontal
disease. This organism is commonly
recovered from different infections in humans and animals. It is a key
component of periodontal plaque due to its abundance and its ability to live in
community with other bacteria in the oral cavity
Other conditions caused by Fusobacterium
Dr. Yiping Han has been tracking this bacteria for years.
Research has shown that this bacteria travels
through the body and attaches itself to blood vessels Dr
Han has and implicated it in low birth weight, amniotic fluid sepsis, and fetal
The Colon Cancer Connection
to Dr. Yipping Han, it has been reported that there were a striking number of
the bacteria in colon cancer tumor samples, published concurrently by separate
research groups in the journal Genome Research.“There
were huge numbers of [the bacteria] in the tumor tissues,” Han said. “But
we didn't know if it was a cause or a consequence of the cancer.
Using a test-tube experiment with samples of colon cancer tumors, Han’s lab
mixed in Fusobacterium, and found that the cancer cells grew faster. “But if we
knocked out [FadA] ( a component of the bacteria's metabolism),
it didn't stimulate the growth anymore,” Han said. Dr Han's lab took
their experiments in vivo, and injected Fusobacterium into mice who had colon
cancer tumors. As expected, the bacteria increased the tumor growth rate.
believes that there are markers for Fusobacterium nucleatum that doctors can
track to help in early diagnosis of tumors and Colorectal Cancer. More research
needs to be done to develop this testing procedure.
Go to the
dentist regularly and have your teeth professionally cleaned. In addition, In
addition if you are told you have gum disease, you need to get it treated. Also
adults over age 40 should have routine colonoscopy done every 5 years.
To The Body.
is truly the gateway to your body and it is important to keep it healthy.In my
previous blog, I listed several other conditions related to gum disease
including Alzheimer's, heart attack, stroke, diabetes, osteoporosis and
respiratory disease. Now you can include low birth weight, fetal sepsis, fetal
death, and colon cancer.
Born in the Midwest.
Married with 6 children and 3 grandchildren. Attended Maine West High School, Harper Jr College, Northern Illinois University, the University of Illinois College of Dentistry. Practice in Crystal Lake, Illinois.