Colon Cancer is Common and Deadly
It is the
second leading cause of death by cancer in the United States. . In 2009, the most recent year data was available, 136,717 people in the United
States were diagnosed with the disease. Overall, the lifetime risk of developing colorectal cancer is about 1 in
20 (5%).
Gum Disease and
Fusobacteruim nucleatum
The connection is Fusobacterium nucleatum. Fusobacterium
nucleatum is an oral bacteria, common to the human oral cavity, that plays a role in periodontal
disease. This organism is commonly
recovered from different infections in humans and animals. It is a key
component of periodontal plaque due to its abundance and its ability to live in
community with other bacteria in the oral cavity
Other conditions caused by Fusobacterium
nucleatum
Dr. Yiping Han has been tracking this bacteria for years.
Research has shown that this bacteria travels
through the body and attaches itself to blood vessels Dr
Han has and implicated it in low birth weight, amniotic fluid sepsis, and fetal
death.
The Colon Cancer Connection
According
to Dr. Yipping Han, it has been reported that there were a striking number of
the bacteria in colon cancer tumor samples, published concurrently by separate
research groups in the journal Genome Research.“There
were huge numbers of [the bacteria] in the tumor tissues,” Han said. “But
we didn't know if it was a cause or a consequence of the cancer.
Using a test-tube experiment with samples of colon cancer tumors, Han’s lab
mixed in Fusobacterium, and found that the cancer cells grew faster. “But if we
knocked out [FadA] ( a component of the bacteria's metabolism),
it didn't stimulate the growth anymore,” Han said. Dr Han's lab took
their experiments in vivo, and injected Fusobacterium into mice who had colon
cancer tumors. As expected, the bacteria increased the tumor growth rate.
Now What?
Dr. Han
believes that there are markers for Fusobacterium nucleatum that doctors can
track to help in early diagnosis of tumors and Colorectal Cancer. More research
needs to be done to develop this testing procedure.
What Can
You Do?
Go to the
dentist regularly and have your teeth professionally cleaned. In addition, In
addition if you are told you have gum disease, you need to get it treated. Also
adults over age 40 should have routine colonoscopy done every 5 years.
Gateway
To The Body.
The mouth
is truly the gateway to your body and it is important to keep it healthy.In my
previous blog, I listed several other conditions related to gum disease
including Alzheimer's, heart attack, stroke, diabetes, osteoporosis and
respiratory disease. Now you can include low birth weight, fetal sepsis, fetal
death, and colon cancer.
Call for an appointment today!
815 459 2202
Dr. Neal answers all of your questions about Gum Disease at Crystal Lake Dental Associates.
Your comments are welcome
Call for an appointment today!
815 459 2202
Dr. Neal answers all of your questions about Gum Disease at Crystal Lake Dental Associates.
Your comments are welcome
A new study has revealed that bacteria can contribute to colorectal cancer. Nucleatum is a bacterium that is commonly found in dental plaque and it is associated with colorectal cancer. Therefore people should take care about their oral health and must try to maintain good oral hygiene.
ReplyDeleteBy Colorado Springs Dentist
Very good work really it will useful to all people thank you for posting this blog.
ReplyDeleteTeeth problems